Sung Ro Lee,Kevin Shrestha,Jackson Staggers,Peng Li,Sameer M. Naranje,Ashish Shah.[J].中华创伤杂志英文版,2018,21(6):329-332
Impact of time to surgery from injury on postoperative infection and deep veinthrombosis in periprosthetic knee fractures
  
DOI:10.1016/j.cjtee.2018.03.005
KeyWord: Total knee arthroplastyPeriprosthetic fractureKneeArthroplastyPostoperative wound infectionDeep vein thrombosis
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Author NameAffiliation
Sung Ro Lee University of Alabama at Birmingham, 1313 13th Street South, Suite 226, Birmingham, AL, 35205, United States 
Kevin Shrestha University of Alabama at Birmingham, 1313 13th Street South, Suite 226, Birmingham, AL, 35205, United States 
Jackson Staggers University of Alabama at Birmingham, 1313 13th Street South, Suite 226, Birmingham, AL, 35205, United States 
Peng Li University of Alabama at Birmingham, 1313 13th Street South, Suite 226, Birmingham, AL, 35205, United States 
Sameer M. Naranje University of Alabama at Birmingham, 1313 13th Street South, Suite 226, Birmingham, AL, 35205, United States 
Ashish Shah University of Alabama at Birmingham, 1313 13th Street South, Suite 226, Birmingham, AL, 35205, United States 
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Abstract:
      Purpose: Periprosthetic fracture (PPF) is a serious complication that occurs in 0.3%-2.5% of all total knee arthroplasties used to treat end-stage arthritis. To our knowledge, there are no studies in the literature that evaluate the association between time to surgery after PPF and early postoperative infections or deep vein thrombosis (DVT). This study tests our hypothesis that delayed time to surgery increases rates of postoperative infection and DVT after PPF surgery. Methods: Our study cohort included patients undergoing PPF surgery in the American College of Surgeons National Surgical Quality Improvement Program database (2006-2015). The patients were dichotomized based on time to surgery: group 1 with time 2 days and group 2 with time >2 days. A 2-by-2 contingency table and Fisher's exact test were used to evaluate the association between complications and time to surgery groups, and multivariate logistic regression was used to adjust for demographics and known risk factors. Results: A total of 263 patients (80% females) with a mean age of 73.9 ± 12.0 years were identified receiving PPF surgery, among which 216 patients were in group 1 and 47 patients in group 2. Complications in group 1 included 3 (1.4%) superficial infections (SI), 1 (0.5%) organ space infection (OSI), 1 (0.5%) wound dehiscence (WD), and 4 (1.9%) deep vein thrombosis (DVT); while complications in group 2 included 1 (2.1%) SI, 1 (2.1%) OSI, 1 (2.1%) DVT, and no WD. No significant difference was detected in postoperative complications between the two groups. However, patients in group 2 were more likely (p=0.0013) to receive blood transfusions (57.5%) than those in group 1 (32.4%). Conclusion: Our study indicates patients with delayed time to surgery have higher chance to receive blood transfusions, but no significant difference in postoperative complications (SI, OSI, WD, or DVT) between the two groups.
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